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Three-dimensional confocal fluorescent images with unsurpassed
resolution and contrast—now obtainable at a minimum cost for use in broad
bio-research applications
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Nikon proudly introduces a universal confocal microscope system that is ultra-compact
and lightweight, yet provides confocal images of the highest quality in its class.
With the C1, confocal microscopy is now a mainstream technique affordable by all. |
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Highest quality optical performance
A successful fusion of Nikon's optical and electronics technologies, the C1's
resolution, contrast, and fluorescent image brightness are all top-class and "State
of the Art." Image sizes of up to 2K by 2K at 12 bit image depth can be easily
scanned.
Interchangeable filters
Changing the filter to match the fluorescent dyes you want to use is simple and
quick, enabling the use of the latest probes or dyes available today.
3-channel
simultaneous detection
The C1 supports almost any imaging technique required today, including simultaneous
3-channel fluorescence, 3-channel plus DIC, time-lapse recording, and spatial
analysis.
Modular design saves space and facilitates upgrading
All main components are modular including the laser box, scanner head, and detector
module, saving desk space and allowing easy upgrades and maintenance.
Intuitive
software promotes multifaceted microscopic analysis
The C1's Graphical User Interface (GUI) is extremely simple and intuitive. From
the time of initial use, you may never need to refer to the manual for typical
operation.
Easy to configure, easy to operate
Each of the modules is pre-calibrated, eliminating the need for calibration during
setup. Just connect the modules you need, and you are ready for optimal image
capture.
Compact design
With a small footprint, the C1 does not get in the way of other lab equipment.
Consequently, there is plenty of work space left around the microscope. |
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| Unprecedented image quality |
Why are the C1’s images so good?
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Stray light, which is usually generated in the scanner head and
common in some other designs, is thoroughly eliminated, while reflection loss
on the I/O ends of the optical fiber is minimized. This makes it possible to obtain
images with extremely high contrast and photon efficiency. |
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 Fluorescence
transmission efficiency has been dramatically improved to obtain fluorescent images
3 times brighter than previous Nikon models. This, coupled with the use of high
quantum-efficiency photomultiplier tubes, gives clear, sharp images even with
fluorescent specimens that in the past were too dim to observe. |
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Signal-to-noise ratio has been increased 7-fold (compared to previous
Nikon models), resulting in a significantly improved image quality. |
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12-bit digitization pixel depth ensures the quality, dynamic range
and sensitivity that is required of a 4-megapixel image . |
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Universal scanner head
The scanner head can be easily mounted on either upright or inverted microscopes
to support a wide range of applications. |
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| C1 system configured with E600 microscope
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C1 system configured with TE2000 microscope |
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 Various
laser types
The wider range of excitation light wavelengths facilitating the use of an increased
number of fluorochromes in research has increased the demand for the number of
lasers available on the market. The C1 comes with a series of lasers supporting
almost every fluorescent dye used in research today. |
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Wide choices of fluorochromes
Besides the excitation lasers, a full selection of emission filters are available
to support a wide range of fluorescence observation needs. The detection module
is supplied with appropriate dichroic mirrors, allowing simultaneous 3-color observation
of fluorescence images of specimens prepared for 3-color imaging . |
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| Operation is a breeze—and customizing
just as simple |
| Live images can be captured with ease |
 All
settings and procedures required for live image capture—fundamentals in confocal
microscopy—can be viewed in a single window, eliminating the need for the
operator to switch between many windows. The operation panel gives you an at-a-glance
picture of all important settings including scan mode, scan speed, pixel size,
zoom/pan, PMT settings, pinhole, shutter, and color image look-up table. With
the C1, scanning modes are expanded from 2D (XY, YZ, XZ), to 3D (XYZ, Xyt), and
even further to 4-dimensional (XYZt) scans. |
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Time-lapse recording is also a simple matter
All required procedures for time-lapse recording, including the setting of inter-cycle
times, frame intervals, and the number of images to be captured can be provided
in a single window for quick, easy operation. Image capture via sync-control from
automated accessories or connected electrophysiology equipment is also possible.
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